MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid peptide encoded within the mitochondrial genome. It is the first mitochondria-derived peptide shown to regulate nuclear gene expression and cellular metabolism in laboratory models. MOTS-C is studied for its effects on AMPK activation, glucose uptake signaling, fatty acid oxidation pathways, and metabolic homeostasis.
Research Applications: AMPK activation research, mitochondrial-nuclear signaling, glucose metabolism pathway modeling, fatty acid oxidation signaling studies, metabolic homeostasis analysis.
For research use only. Not for human consumption. This product is intended solely for laboratory and scientific research by qualified professionals.
Certificate of Analysis
Batch Number: VI2120251117-10
Date of Analysis: November 2025
Download COA (PDF)
Each batch of our products undergoes rigorous quality testing including HPLC purity analysis and mass spectrometry verification. COAs are available for all current and recent batches.
Published Research References
The following peer-reviewed publications reference this peptide in research contexts. These citations are provided for informational purposes only and do not constitute claims of efficacy.
Research references for this product are being compiled. Check back soon or contact us for research literature related to this peptide.
Handling & Storage Guidelines
| Storage (Lyophilized) | -20°C, protected from light and moisture |
| Storage (Reconstituted) | 2-8°C for up to 14 days; -20°C for long-term storage. Avoid repeated freeze-thaw cycles. |
| Reconstitution | Reconstitute in sterile bacteriostatic water or appropriate buffer per your research protocol. |
| Handling | Handle under aseptic conditions in a laminar flow hood when possible. Use appropriate PPE. |
| Shipping | Shipped with cold packs. Inspect packaging upon receipt and transfer to proper storage immediately. |
Laboratory Use OnlyThis product is not intended for human or animal administration. Handle in accordance with your institution's safety protocols and applicable regulations.
